解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Over the last years the reality surrounding HIV-infection has undergone a considerable change with regard to the life expectancy of patients, and the plans they can make for their lives. Because the majority of the HIV positive population is of reproductive age, one of these plans might be to have children, often as a...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2001-07-30 00:00:00
abstract:BACKGROUND/OBJECTIVE:The continuous interaction of blood with artificial contact surfaces under cardiopulmonary bypass can lead to a substantial damage of blood cells and plasma factors. Surface biopolymers in oxygenation systems can help increasing the hemocompatibility, often combined with anticoagulative agents such...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2001-07-30 00:00:00
abstract::Pentalogy of Fallot is a rare cyanotic congenital heart disease characterized by biventricular origin of the aorta above a large ventricular septal defect, obstruction of the pulmonary outflow, right ventricular hypertrophy (tetralogy of Fallot), and an atrial septal defect. Mortality due to syncope, arrhythmia or con...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2001-06-28 00:00:00
abstract:OBJECTIVE:The aim of this study was to examine the influence of immuno modulating agents like bromelain and trypsin (e.g. Wobenzym on granulocyte and monocyte functions in healthy volunteers and patients with disorders of the humoral immuno system X-linked agammaglobulinaemia (XLA) and common variable immuno deficiency...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2001-05-29 00:00:00
abstract:UNLABELLED:Prolonged immobilization of severely ill, bed-ridden patients results in formation of pressure ulcers following inappropriate tissue blood perfusion, and local activation of leukocyte - endothelial cell interactions (L/EC). Various treatment modalities were implemented to improve local microcirculation with ...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2001-04-20 00:00:00
abstract:BACKGROUND:Prophylaxis efforts for the maintenance of tooth health led to a distinctive decrease in caries frequency with children and young persons. Because the toothbrush can still be described as the most important oral hygiene aid, possible differences between the effectivity of electric and manual toothbrushes sho...
journal_title:European journal of medical research
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2001-01-29 00:00:00
abstract::Infectious diseases remain a major cause of morbidity and mortality in the year 2000. 17 million deaths per year or roughly a third of all deaths are caused by infections. Infectious diseases also pose a serious economic threat. While many well-established pathogens have not been contained several new infectious agent...
journal_title:European journal of medical research
pub_type: 总体
doi:
更新日期:2000-11-30 00:00:00
abstract::The shared care paradigm is the current response to the crisis of industrial countries' health systems. The underlying information systems have to meet the shared care paradigm of communication and co-operation between all the partners involved in. This communication and co-operation must be provided in a secure way. ...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2000-08-18 00:00:00
abstract::A 70-year-old woman with a progressive dominant hemisphere syndrome but only mild hemiparesis and a normal brain scan (>3 hours from stroke onset) showed angiographic occlusion of the left anterior cerebral artery and the middle cerebral artery at its trifurcation with preservation of the rolandic artery. Intra-arteri...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2000-07-19 00:00:00
abstract::CMV infection is common in pediatric HIV-1 infected patients. We present a case report, to our knowledge the first pediatric patient, in which Addison-disease due to CMV was suspected during lifetime. We want to point out the importance of routine clinical and laboratory follow up once a HIV-1 infected child is shown ...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2000-06-20 00:00:00
abstract::The current report describes the experience from the Frankfurt AIDS Cohort Study with patients suffering from renal failure. The clinical data of 4993 HIV-infected patients between 1983 and 1998 were analyzed retrospectively. Patients were seen at least twice a year and clinical features, routine laboratory results, i...
journal_title:European journal of medical research
pub_type: 杂志文章,评审
doi:
更新日期:2000-05-23 00:00:00
abstract:BACKGROUND:The pathogenesis of central retinal artery occlusions (CRAO) varies, depending upon the underlying disease. An embolic origin of an occlusion often occurs. PATIENT AND METHODS:A 50-year-old man with an occlusion of the left internal carotid artery was examined because of a left central retinal artery occlus...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2000-04-19 00:00:00
abstract::We report the case of a 64-year old woman with severe attacks of allergic alveolitis occurring frequently independent of a concrete place. These attacks were regularely preceded by diarrhoe. Laboratory data showed marked leukopenia and circulating Candida albicans (C.a.)-antigen. Bronchoalveolar lavage revealed an inc...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2000-03-27 00:00:00
abstract::Fluid shift after entering into microgravity, but also under equivalent flight conditions leads to enormous increase of intraocular pressure. To assess this precisely position - and gravity independent, handsome, automatic tonometers have been developed (German-Spacelab D1-Mission, German-Spacelab D2-Mission, German-R...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2000-01-26 00:00:00
abstract::Human Immunodeficiency virus can affect the peripheral (PNS) and central nervous system (CNS). In the ART / HAART era especially the CNS is said to be a virus reservoir so that neurologists have to be more and more integrated in therapy planning. Therefore the present paper describes neurological indications for ART, ...
journal_title:European journal of medical research
pub_type: 杂志文章,评审
doi:
更新日期:1999-11-22 00:00:00
abstract::Experiments in space have shown that T lymphocyte function is altered in more than 50% of space crew members. There is strong evidence that such effect is due to stress rather than to weightlessness per se. However the health of astronauts was never threatened so far. Experiments in-vitro with cultures of human periph...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1999-09-09 00:00:00
abstract::In 1973 copper-associated liver disease was first described in an Australian boy of non-Indian origin who died at the age of 15 months with liver cirrhosis. At necropsy the hepatic copper concentration was excessively high (> 300 mg/g dry weight). It was shown that the boy s disease was caused by consumption of copper...
journal_title:European journal of medical research
pub_type: 历史文章,杂志文章
doi:
更新日期:1999-06-28 00:00:00
abstract::Basic research: Perfluorocarbons and the Pulmonary Surfactant System - Perfluorocarbons in the Treatment of Pneumonia - Inertance of the Respiratory System during Partial Liquid Ventilation - Alveolar Dead Space and Partial Liquid Ventilation - Partial Liquid Ventilation and Prevention of Cerebral Damage - New therapi...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1999-05-26 00:00:00
abstract::Tooth-colored resin-based restoration materials have gained enormous significance in recent decades. Since the composites presently available still evidence various weaknesses, intensive research continues concerning them. In this study we tested the biocompatibility of six resin-based materials (Charisma, Solitaire, ...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1999-04-27 00:00:00
abstract::In the course of infection by the Human Immunodeficiency Virus (HIV) typical changes of inflammatory periodontal diseases can arise. The prevalence of these illnesses may be up to 5%. The HIV-associated periodontal diseases include linear gingival erythema (LGE), necrotizing ulcerative gingivitis (NUG) and necrotizing...
journal_title:European journal of medical research
pub_type: 杂志文章,评审
doi:
更新日期:1999-03-26 00:00:00
abstract::Therapeutic options are limited for patients refractory to triple therapy with two reverse transcriptase inhibitors and one protease inhibitor. Preliminary results showing favorable effects of protease inhibitor combination therapy with nelfinavir and saquinavir due to inhibition of metabolism by cytochrome P450 (CYP4...
journal_title:European journal of medical research
pub_type: 临床试验,杂志文章
doi:
更新日期:1999-02-25 00:00:00
abstract::Long-term pneumotachographic measurements in newborns are hampered by the apparatus dead space, which can be functionally eliminated by a constant bias flow (flow-through technique). In a clinical study the influence of this bias flow was investigated. - In 80 infants (group 1:20 healthy controls, group 2: 30 infants ...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1999-01-26 00:00:00
abstract::The gum resin of Boswellia serrata, known in Indian Ayurvedic system of medicine as Salai guggal, contains boswellic acids, which have been shown to inhibit leukotriene biosynthesis. In a double-blind, placebo-controlled study forty patients, 23 males and 17 females in the age range of 18 - 75 years having mean durati...
journal_title:European journal of medical research
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1998-11-17 00:00:00
abstract::Soot FR 101, Printex 90 and Chrysotile B are frequently found in indoor air pollutants phagocytized by alveolar macrophages (AM) involved in inflammatory pulmonary processes as, e.g. in cytokine secretions. The transcription factor NF-kappaB has a role in the trans-duction pathway of proinflammatory cytokines like IL-...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1998-09-17 00:00:00
abstract::Targeted intrapulmonary delivery of drugs may reduce systemic toxicity, improve treatment efficacy, but inhaled drugs may also interfere with pulmonary surfactant function. We hypothesized that the lipophilic drug amphotericin B used to treat or prevent pulmonary infections with aspergillus species, might destroy surf...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1998-08-18 00:00:00
abstract:OBJECTIVES:The present study was carried out to assess compliance rates with annual colorectal cancer screening for fecal occult blood, and to identify the subjects with higher priority in health education to increase screen compliance. DESIGN AND SETTING:A screening program for colorectal cancer was conducted between...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1998-07-20 00:00:00
abstract::Intercellular adhesion molecule-1 (ICAM-1) plays an important role in inflammatory diseases. It is believed that its soluble form (sICAM-1) might be a serum parameter of inflammatory activity with possible relevance in granulomatous disorders. To evaluate this role we measured sICAM-1 by ELISA in serum and shedding of...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1998-06-17 00:00:00
abstract::Photoplethysmography enables non-invasive investigation of the volume pulse in the microvasculature of patients. We previously have shown that time-discrete analysis enables identification of highly reproducible characteristics of the volume pulse in absolute values. The method would be of particular interest, if the ...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1998-05-12 00:00:00
abstract::In this study a potential influence of diatomaceus earth to lower blood cholesterol was investigated. During 12 weeks we monitored serum lipid concentrations in 19 healthy individuals with a history of moderate hypercholesterinemia (9 females, 10 males, aged 35 - 67 years). Individuals administered orally 250 mg diato...
journal_title:European journal of medical research
pub_type: 临床试验,杂志文章
doi:
更新日期:1998-04-08 00:00:00
abstract::Determination of fecal excretion of the serum proteinase inhibitor alpha(1)-antitrypsin (AAT) is established for quantification of intestinal protein loss. It was demonstrated to be increased both in quiescent and in active inflammatory bowel diseases (IBD, Crohn's disease and ulcerative colitis). The (patho)physiolog...
journal_title:European journal of medical research
pub_type: 杂志文章,评审
doi:
更新日期:1998-02-21 00:00:00
abstract::The influence of heparin on Polymorphonuclear (PMN s) leukocytes was investigated using a new whole-blood cytofluorometric method (patent granted for the test with the number P 4334935.8-41) with Candida albicans and Staphylococcus aureus as test microorganisms. After comparing the effect of equal volumes of two widel...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1997-12-31 00:00:00
abstract::A 62-year-old white male presented with facial erythema and jugular vein distension in upright position which progressed to cyanosis and facial edema while keeping both arms elevated (Pemberton sign). A CT scan revealed a large substernal goiter as the cause of superior vena cava syndrome. Symptoms and signs disappear...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1997-11-28 00:00:00
abstract::In ten cystic fibrosis patients and nine age-matched controls, renal function was determined before and after infusion of secretin. Under baseline conditions creatinine excretion and clearance were significantly elevated, exclusively due to those patients who were homozygous for the DF508 mutation (153 vs 132 ml/min*1...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1997-10-30 00:00:00
abstract::A serological diagnosis (ELISA test) was carried out of infections by Helicobacter pylori in 1200 young males (recruits in the Polish Army) and the influence of selected epidemiologico-clinical factors (civil status, place of residence, profession, economical conditions, tobacco smoking, consumption of alcohol, diseas...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1997-08-28 00:00:00
abstract::As it has been reported that basic fibroblast growth factor (bFGF) is a circulating peptide and bFGF gene expression is increased after myocardial ischemia, this study was designed to investigate the serum levels of bFGF in patients with acute myocardial infarction (AMI). Using a bFGF enzyme-linked immunoassay, bFGF l...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1997-07-28 00:00:00
abstract::The history and todays knowledge on the pathogenesis of arteriosclerosis emphasizing the importance of cholesterol concentration in plasma for the development of atherosclerosis is summarized. For proving the lipid hypothesis careful patient observation and new findings of molecular biology have added important inform...
journal_title:European journal of medical research
pub_type: 杂志文章,评审
doi:
更新日期:1997-06-16 00:00:00
abstract::Exposure to high concentrations of oxygen is known to induce changes in lung function through effects on several pulmonary cell types, including alveolar macrophages (AM). In this study, we studied the in vitro effects of hyperoxia on the release of proinflammatory cytokines and the expression of surface receptors in ...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1997-04-21 00:00:00
abstract::A number of neurodegenerative diseases including Parkinson's disease (PD) have been shown to be associated with polymorphic variants of mitochondrial DNA. The A4336G mutation in the tRNA(Gln) gene was reported to occur at a higher frequency in individuals with Parkinson's disease and Alzheimer's disease (AD) than in a...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1997-03-24 00:00:00
abstract::Infant formulas containing medium chain triglycerides (MTC) have been used for the nutritional management of infants with fat malabsorption. The optimal proportion of MTC in the formula remains to be determined. Three infant formulas with varying proportion of MTC in the fat blend were studied in children with cystic ...
journal_title:European journal of medical research
pub_type: 杂志文章,评审
doi:
更新日期:1997-02-21 00:00:00
abstract::The aim of the study was to investigate whether cholecystokinin, neurotensin, and cholinergic mechanisms act as mediators of bile salt-stimulated exocrine pancreatic secretion. Ten fasting healthy subjects provided with a double-lumen tube received 2, 4, and 6 g cattle bile and 200, 400, and 600 mg Na-taurodeoxycholat...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00